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KMID : 0387720160270010079
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Korean Journal of Blood Transfusion
2016 Volume.27 No. 1 p.79 ~ p.83
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A Case of Hemolytic Transfusion Reaction Attributable to Anti-Jkb Abolished in the Enzyme Phase Reaction
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송새암:Song Sae-Am
오승환:Oh Seung-Hwan/이자영:Lee Ja-Young/성성경:Sung Sung-Kyung/신정환:Shin Jeong-Hwan/김혜란:Kim Hye-Ran/전경란:Jun Kyung-Ran/이정녀:Lee Jeong-Nyeo
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Abstract
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We report a case of an intravascular hemolytic reaction attributable to anti-Jkb antibodies that were not detected using an enzyme phase antibody identification test. A 61-year-old male who had received two units of red blood cells was admitted to the emergency room because his urine was dark. LISS/Coombs gel column agglutination tests suggested the presence of anti-Jkb and anti-E antibodies. However, his serum was negative for the Jkb antigen when an enzyme phase test was performed. A positive reaction was evident, however, when EDTA-treated plasma was tested; this excluded any possible complement-mediated reaction. The patient was diagnosed with an intravascular hemolytic transfusion reaction, caused by anti-Jkb, and was later discharged without specific complications after receiving antigen-negative blood transfusions.
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KEYWORD
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Kidd Blood-Group System, Enzyme, EDTA, Hemolytic transfusion reaction
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